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Geodon Antidepressant : Ziprasidone

Brand Name : Ziprasidone

ZIPRASIDONE (Geodon®) treats the symptoms of schizophrenia. Such symptoms may include hearing or seeing things that others do not, suspiciousness of others, mistaken beliefs, or withdrawal from normal activities, family and friends. This drug may also help treat some other emotional problems, such as bipolar disorder (also known as manic depression). Generic ziprasidone capsules are not yet available. Geodon (ziprasidone) is an antipsychotic medication—one of a group called "atypical" to distinguish these newer drugs from older medications. The FDA approved Geodon as a treatment for schizophrenia in 2001. It helps manage schizophrenia’s "positive" symptoms, such as auditory hallucinations, delusions, and thought disturbances. Geodon may also help in treating the "negative" symptoms of schizophrenia, which include social withdrawal, apathy, lack of motivation, and an inability to experience pleasure. Geodon is presently being studied for the treatment of bipolar disorder. Geodon is used in the treatment of the crippling mental disorder known as schizophrenia. Researchers believe that it works by opposing the action of serotonin and dopamine, two of the brain's major chemical messengers. Because of its potentially serious side effects, Geodon is typically prescribed only after other medications have proved inadequate.

Geodon is usually taken in capsule form. An injectable version is available for quick relief of agitated patients. Injectable Geodon is generally used for no more than a few days.

Uses of Geodon

Geodon is an antipsychotic medicine. Antipsychotic medicines are used to treat symptoms of schizophrenia that may include: 

  • hearing voices, seeing things, or sensing things that are not there 
  • mistaken beliefs
  • unusual suspiciousness 
  • becoming withdrawn from family and friends 
  • Geodon is used to manage the symptoms of psychotic disorders such as schizophrenia that may include hearing voices; seeing things or sensing things that are not there; mistaken beliefs; unusual suspiciousness; or becoming withdrawn from family and friends.
  • Geodon is also used to treat bipolar mania.
  • Geodon may also be used for purposes other than those listed in this medication guide.

How to Take Geodon

  • Geodon capsules should be taken twice a day with food.
  • Take each oral dose with a full glass of water.
  • Take Geodon with food at the same time each day.
  • Continue to take Geodon, even if your symptoms have improved. Continuous treatment may prevent the return of symptoms. Do not stop taking this medication without first talking to your doctor.
  • Store Geodon at room temperature away from moisture, light, and heat.

What are the Side Effects of Geodon Medication

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Geodon. More common side effects may include:

  • Accidental injury
  • cold symptoms
  • constipation
  • cough
  • diarrhea
  • dizziness
  • drowsiness
  • dry mouth
  • indigestion
  • muscle tightness
  • nausea
  • rash
  • stuffy and runny nose
  • upper respiratory infection
  • vision problems
  • weakness
  • Abdominal pain
  • abnormal body movements
  • abnormal ejaculation
  • abnormal secretion of milk
  • abnormal walk
  • abnormally low cholesterol
  • agitation
  • amnesia
  • anemia
  • bleeding gums
  • bleeding in the eye
  • blood clots
  • blood disorders
  • blood in urine
  • body spasms
  • breast development in males
  • bruising or purple spots
  • cataracts
  • chest pain
  • chills

Warnings and precautions before taking Geodon Medication

  • Remember that Geodon can cause dangerous--even fatal--heartbeat irregularities. Warning signs include dizziness, palpitations, and fainting. Tell your doctor immediately if you experience any of these symptoms. Be careful to avoid drugs that prolong the QT interval of the heartbeat. Check with your doctor before combining any other medication with Geodon.
  • Particularly during the first few days of therapy, Geodon can cause low blood pressure, with accompanying dizziness, fainting, and rapid heartbeat. Tell your doctor if you experience any of these side effects. To minimize such problems, your doctor will increase your dose gradually. If you are prone to low blood pressure, take blood pressure medicine, become dehydrated, or have heart disease or poor circulation in the brain, use Geodon with caution.
  • Geodon may cause drowsiness and can impair your judgment, thinking, and motor skills. Use caution while driving and don't operate potentially dangerous machinery until you know how this drug affects you.
  • Geodon poses a very slight risk of seizures, especially if you are over age 65, have a history of seizures, or have Alzheimer's disease.
  • Drugs such as Geodon sometimes cause a condition called Neuroleptic Malignant Syndrome. Symptoms include high fever, muscle rigidity, irregular pulse or blood pressure, rapid heartbeat, excessive perspiration, and changes in heart rhythm. If these symptoms appear, tell your doctor immediately. You'll need to stop taking Geodon while the condition is under treatment.
  • There also is the risk of developing tardive dyskinesia, a condition marked by slow, rhythmical, involuntary movements. This problem is more likely to occur in mature adults, especially older women. When it does, use of Geodon is usually stopped.
  • Geodon can suppress the cough reflex; you may have trouble clearing your airway. Some people taking Geodon also develop a rash. Tell your doctor when this happens. If the rash doesn't clear up with treatment, you may have to discontinue the drug.
  • Other antipsychotic medications have been known to interfere with the body's temperature-regulating mechanism, causing the body to overheat. Although this problem has not occurred with Geodon, caution is still advisable. Avoid exposure to extreme heat, strenuous exercise, and dehydration. There also is a remote chance that this medication may cause abnormal, prolonged and painful erections.

What drugs may interact with Geodon Tablet

Remember that you must never combine Geodon with any drug that prolongs the part of the heartbeat known as the QT interval (see "Most important fact about this drug"). Check with your doctor or pharmacist if you have any doubts about a drug you're taking.

If Geodon is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Geodon with the following:

  • Carbamazepine (Tegretol)
  • Certain blood pressure medications
  • Drugs that boost the effects of dopamine such as Mirapex, Parlodel, Permax, and
  • Requip
  • Drugs that affect the brain and nervous system, such as sedatives, tranquilizers, and
  • antidepressants
  • Ketoconazole (Nizoral)
  • Levodopa (Larodopa, Sinemet)

What to do if you take Overdose of Geodon ?

Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical help immediately. Symptoms of Geodon overdose may include:

  • Drowsiness
  • slurred speech
  • high blood pressure

  • dizziness
  • increased heart rate
  • fainting
  • sweating
  • fever
  • muscle spasms
  • hands
  • tongue

How to Store Geodon ?

Keep this medication in the container it came in, tightly closed, and out of the reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.


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Disclaimer: is designed to help and support for people who have depression or are depressed. It is not intended to treat, diagnose, cure, or prevent any psychiatric, psychological or mental diseases. Always take the advice of professional health care for specific medical advice, diagnoses, and treatment. We will not be liable for any complications, or other medical accidents arising from the use of any information on this web site.